Scientist l - Immunology Discovery
Company Description
About AbbVie AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us atwww.abbvie.com. Follow @abbvie onLinkedIn,Facebook,Instagram,XandYouTube.
Job Description
We are currently seeking a highly motivated and passionate scientist to join our team in Immunology Discovery based in Cambridge MA. This lab-based individual will be responsible for cellular/molecular functional assays to support novel target identification/validation and early portfolio programs within GI immunology. The scientist is expected to read and adapt scientific literature and internal protocols to accomplish assignments and demonstrate broad and versatile technical expertise within immunology. The position requires ability to work independently, deliver reliable results in a timely manner, have excellent technical, written and oral communication skills and work very well in a collaborative team environment. Key responsibilities - Independently develop, execute and analyze functional assays using human cell lines and primary cells for screening molecules and testing hypothesis.
- Perform advanced molecular and cellular biology techniques (including but not limited to FACS, ELISA, MSD, HTRF) to measure cellular activation, differentiation and effector molecule production.
- Isolate, culture or differentiate immune cells (PBMCs, T cells, myeloid cells) from human and mouse blood products or tissues.
- Require minimum supervision for established protocols and routine methods.
- Implement and innovate new experimental protocols/techniques as needed.
- Analyze, interpret, document and report data consistently, concisely and rigorously, both to individual stakeholders and in group settings.
- Demonstrate scientific excellence through dedication to multiple projects with different priority requirements in a fast-paced multi-disciplinary environment,
- Impact projects mostly through lab-based activities
Qualifications
- Bachelors Degree with typically 5 years of relevant industry experience, OR Masters Degreewith typically 2 yearsof relevant industry experience.
- Robust experience with in-vitro cell culture (sterile techniques, handling challenging cell types) and cell-based assays development is required.
- Robust experience with human PBMC functional assays and/or immune cells culture/co-culture assays (T cells and myeloid cells) is required.
- Robust experience in immunoassays including multi-color flow cytometry and ELISA (or MSD, HTRF) is required.
- Experience with mouse tissue processing for immune profiling (not direct mouse handling) is a plus.
- Knowledge of DNA/RNA handling and other molecular biology techniques like PCR, qPCR and Western blotting is a plus.
- Ability to learn new skills and apply them in a fast-paced research environment.
- Creativity, problem-solving, and attention to details.
- Excellent oral and written communication and collaboration skills.
- Ability to work independently as well as in a team.
- Proven flexibility to deal with changing timelines and shifting work priorities.
Additional Information
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law: The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at the timeofthis posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographic location,andwemayultimatelypaymore or less than the posted range. This range may bemodifiedin thefuture. We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees. This job is eligible toparticipatein our short-term incentiveprograms.
Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.The amount and availability of anybonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employeeremainsin the Company's soleandabsolutediscretion unless and until paid andmay bemodifiedat the Companys sole and absolute discretion, consistent withapplicable law. AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled. US & Puerto Rico only - to learn more, visithttps://www.abbvie.com/join-us/equal-employment-opportunity-employer.html US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more: https://www.abbvie.com/join-us/reasonable-accommodations.html
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